How To Ensure Safety While Employing Tramadol For The Elderly?


Why do you need to administer Tramadol for elderly cautiously? With advancing age, the functioning and composition of the body change. And so does Pharmacotherapy requirements and implementation in the elderly.

Old age brings with itself a loss of functional capabilities of most organs, loss of water content, an increase of fat content in the body and a decline in response to receptor stimulation.

The essential standard change in the human body in old age is a contraction in the excretory capacity of the kidney. Some deterioration in the drug metabolism rate is also recorded with advancing age. A decrease in the cardiovascular system's sensitivity to beta-adrenergic agonists and antagonists and an increase in the incidence of orthostatic episodes in response to blood pressure-lowering drugs is observed.

Tramadol, an opioid analgesics, affects the functioning of the brain receptors and changes the receptor's perception of pain. The central nervous system becomes particularly vulnerable in the older people rendering them increased responsiveness to all kinds of drugs. So, there exists a different dosage of Tramadol for elderly.



Medications like opioids, anaesthetics, and anticonvulsants affect brain functioning and must be used with extreme caution. The dosage requirement of any medicinal drug in the old age group is clinically determined, and medications should be administered to older adults accordingly.

The extended-release-tablet formulation of Tramadol is administered carefully to treat moderate to severe chronic pain in the elderly. Significant geriatric-specific problems were identified in various studies that led to the limitation in the use of Tramadol for elderly.

 A lot of unwanted side effects like lightheadedness, fainting or dizziness, stomach upset are likely to appear in elderly patients due to weakness and age-induced liver, heart, kidney, or lung problems.

 Geriatric dosage varies significantly in strength and form than the general dosage. So, therapy for the people under 65 years of age initiates at the lower end of the dosing range. If the patient is over 75 years of age, the dose should not exceed 300 mg/day. For the treatment of patients below the age of 75, administer the release formulation of Tramadol with extreme caution. Avoid crushing, chewing, splitting or dissolving the extended-release tramadol capsule.

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